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start [2017/06/29 12:57]
miranda [Recent Highlights]
start [2019/09/17 10:56] (current)
miranda [Recent Highlights]
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 ======Welcome to the Lim Laboratory====== ======Welcome to the Lim Laboratory======
 +
 +Check out our profile on [[https://​news.ohsu.edu/​2019/​05/​13/​ohsu-physician-scientist-focuses-on-a-good-nights-sleep//​|OHSU News]]
  
 =====Recent Highlights===== =====Recent Highlights=====
-  * 2017: Funded by the [[http://​cdmrp.army.mil/​funding/​phtbi//​|Department of Defense]]+  * 2019: Funded by the [[https://​www.nsf.gov/​funding/​pgm_summ.jsp?​pims_id=505132/​|NSF NCS FOUNDATIONS Award]] 
 +    * //​Integrative approaches to study the role of early life sleep disruption in brain development and autistic behaviors//​ 
 +  * 2018: Funded by the [[http://​www.usuhs.edu/​cnrm//​|Center for Neuroscience and Regenerative Medicine]] and [[http://​cdmrp.army.mil/​phtbi//​|Department of Defense]] 
 +    * //Light therapy in Veterans with TBI to improve sleep and identify biomarkers that relate to improved sleep// 
 +  * 2017: Funded by the [[http://​cdmrp.army.mil/​phtbi//​|Department of Defense]]
     * //​Photosensitivity and pain in complex traumatic brain injury//     * //​Photosensitivity and pain in complex traumatic brain injury//
   * 2016: Funded by the [[http://​www.ohsu.edu/​xd/​about/​foundation/​about/​medical-research-foundation//​|Medical Research Foundation of Oregon]]   * 2016: Funded by the [[http://​www.ohsu.edu/​xd/​about/​foundation/​about/​medical-research-foundation//​|Medical Research Foundation of Oregon]]
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 =====The Team===== =====The Team=====
-//Lab Lunch 2017/06/02// \\ Left to right: * ​[[browse:​personnel:​Matt]], [[browse:​personnel:​Miranda]], [[browse:​personnel:​Natasha]], [[browse:​personnel:​Peyton]], [[browse:​personnel:​Ryan]], [[browse:​personnel:​Carolyn]][[browse:​personnel:​Randall]], [[browse:​personnel:​Mara]], [[browse:​personnel:​Jon]], [[browse:​personnel:​Steve]], [[browse:​personnel:​Alex]]** +====Lab at VA 2019/06/10==== 
-{{:browse:2017_natasha2_sm.jpg?700|}} +Left to right: ​ 
-  * Not pictured: [[browse:​personnel:​Kris]], [[browse:​personnel:​Dennis]], [[browse:​personnel:​Yvonne]], [[browse:​personnel:​Jorge]]+  ​Top row:  **[[browse:​personnel:​Nadir]], [[browse:​personnel:​Carolyn]], [[browse:​personnel:​Cadence]], [[browse:​personnel:​Shannon]], [[browse:​personnel:​Randall]], [[browse:​personnel:​Peyton]]** 
 +  * Bottom row: ** [[browse:​personnel:​Jon]], [[browse:​personnel:​Kris]], [[browse:​personnel:​Kate]], [[browse:​personnel:​Alisha]], [[browse:​personnel:​Miranda]]** 
 +{{ :browse:personnel:​summer2019_sm.jpg?nolink ​|}} 
 +* Not pictured: [[browse:​personnel:​Nick]], [[browse:​personnel:​Selda]], [[browse:​personnel:​Paulina]], [[browse:​personnel:​Jessica]], [[browse:​personnel:​Ashten]] 
  
 +====Lab Lunch 2018/​06/​18====
 +Left to right:
 +  * Top row:   ​** ​ [[browse:​personnel:​Miranda]],​ [[browse:​personnel:​Nadir]],​ [[browse:​personnel:​Kris]],​ [[browse:​personnel:​Alisha]],​ [[browse:​personnel:​Randall]],​ [[browse:​personnel:​Carolyn]],​ [[browse:​personnel:​Chau]],​ [[browse:​personnel:​Tai]],​ [[browse:​personnel:​Alex]]**
 +  * Bottom row: **  [[browse:​personnel:​Jon]],​ [[browse:​personnel:​Natasha]],​ [[browse:​personnel:​Peyton]],​ [[browse:​personnel:​Mara]],​ [[browse:​personnel:​Kendall]],​ [[browse:​personnel:​Dennis]],​ [[browse:​personnel:​Ryan]]**
 +{{ :​browse:​personnel:​lab_photo_18aug.jpg?​nolink |}}
 +* Not pictured: [[browse:​personnel:​Nick]],​ [[browse:​personnel:​Tara]],​ [[browse:​personnel:​Selda]]
 +
 +====Lab Lunch 2017/​06/​02====
 +Left to right: **  [[browse:​personnel:​Matt]],​ [[browse:​personnel:​Miranda]],​ [[browse:​personnel:​Natasha]],​ [[browse:​personnel:​Peyton]],​ [[browse:​personnel:​Ryan]],​ [[browse:​personnel:​Carolyn]],​ [[browse:​personnel:​Randall]],​ [[browse:​personnel:​Mara]],​ [[browse:​personnel:​Jon]],​ [[browse:​personnel:​Steve]],​ [[browse:​personnel:​Alex]]**
 +{{:​browse:​personnel:​lab2017sm2.jpg|}}
 +  * Not pictured: [[browse:​personnel:​Kris]],​ [[browse:​personnel:​Dennis]],​ [[browse:​personnel:​Yvonne]],​ [[browse:​personnel:​Jorge]],​ [[browse:​personnel:​Nick]]
 +
 +//For more, see [[browse:​personnel]]//​
 =====Recent Publications===== =====Recent Publications=====
 +  *Published in //Science Advances// (in press)
 +    * Early life sleep disruption alters the developmental trajectory of cortical parvalbumin and impairs social bonding in prairie voles. ​
 +    * "​[[https://​blogs.ohsu.edu/​researchnews/​2019/​02/​08/​animal-study-connects-early-life-sleep-disruption-to-neurodevelopmental-disorders/​ | OHSU Press Release 2019-Feb]]"​.
 +  *Published in //​Scientific Reports// (in press)
 +    * Strong correlation of novel sleep electroencephalography coherence markers with diagnosis and severity of PTSD.
 +  *Published in //Journal of Clinical Sleep Medicine// (2018)
 +    * Sleep disturbances in Veterans: The impact of chronic pain, traumatic brain injury and post-traumatic stress disorder.
 +  *Published in //​Behavioral Neurology// (2018)
 +    *"​[[https://​www.hindawi.com/​journals/​bn/​2018/​6037015/​abs/​ | Gait and conditioned fear impairments in a novel mouse model of comorbid TBI and PTSD]]"​.
 +  *Published in //Journal of Neurotrauma//​ (2018)
 +    *"​[[https://​www.liebertpub.com/​doi/​abs/​10.1089/​neu.2018.5801 | Blast exposure impairs sensory gating: Evidence from measures of acoustic startle and auditory event-related potentials]]"​.
 +  *Published in //Journal of Cerebral Blood Flow and Metabolism//​ (2018)
 +    *"​[[https://​journals.sagepub.com/​doi/​abs/​10.1177/​0271678X18791632 | Effects of traumatic brain injury on sleep and enlarged perivascular spaces]]"​.
 +  *Published in //​Behavioral Neurology// (2018)
 +    *"​[[https://​www.hindawi.com/​journals/​bn/​2018/​7940832/​abs/​ | Sleep quality and emotion regulation interact to predict anxiety in Veterans with PTSD.]]"​.
 +  *Published in //Frontiers in Neurology// (2018)
 +    *"​[[https://​www.frontiersin.org/​articles/​10.3389/​fneur.2018.00203/​full | The Dynamics of Concussion: Mapping pathophysiology,​ persistence,​ and recovery with causal-loop diagramming]]"​.
 +  *Published in //Journal of Clinical Sleep// (2018)
 +    *"​[[http://​jcsm.aasm.org/​ViewAbstract.aspx?​pid=31324 | Sleep Disturbances in Traumatic Brain Injury: Associations With Sensory Sensitivity]]"​.
 +  *Published in //SLEEP// (2018)
 +    *"​[[https://​academic.oup.com/​sleep/​article/​41/​3/​zsx212/​4791165 | Dietary
 +therapy restores glutamatergic input to orexin neurons after traumatic brain injury in mice]]"​.
 +  *Published in //Frontiers in Neurology// (2017)
 +    *"​[[https://​www.frontiersin.org/​articles/​10.3389/​fneur.2017.00513 | Concussion as a
 +Multi-scale Complex System: An interdisciplinary synthesis of current knowledge.]]"​.
   *Published in //Current Sleep Medicine Reports// (2017)   *Published in //Current Sleep Medicine Reports// (2017)
     * "​[[http://​rdcu.be/​tB1r|Sleep Disturbances in TBI and PTSD and Potential Risk of Neurodegeneration]]"​.     * "​[[http://​rdcu.be/​tB1r|Sleep Disturbances in TBI and PTSD and Potential Risk of Neurodegeneration]]"​.
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   * Published in //Science Translational Medicine// (2013)   * Published in //Science Translational Medicine// (2013)
     * "​[[http://​stm.sciencemag.org/​content/​5/​215/​215ra173.abstract|Dietary therapy mitigates persistent wake deficits in mild traumatic brain injury]]"​.     * "​[[http://​stm.sciencemag.org/​content/​5/​215/​215ra173.abstract|Dietary therapy mitigates persistent wake deficits in mild traumatic brain injury]]"​.
 +
 +For more, see [[browse:​publications]]
  
 =====Research===== ​   =====Research===== ​  
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 [[browse:​Techniques]] used include fluid percussion injury, controlled cortical impact, chronic //in vivo// EEG/EMG recording in freely behaving animals, quantitative EEG signal processing, microdialysis,​ immunohistochemistry,​ electron microscopy, behavior testing in mice and voles, and human sleep studies. [[browse:​Techniques]] used include fluid percussion injury, controlled cortical impact, chronic //in vivo// EEG/EMG recording in freely behaving animals, quantitative EEG signal processing, microdialysis,​ immunohistochemistry,​ electron microscopy, behavior testing in mice and voles, and human sleep studies.
 +
 +=====Contact Us=====
 +
 +[[http://​www.computationalsleep.com/​doku.php/​browse/​contact|Contact Page]]
start.1498766222.txt.gz · Last modified: 2017/06/29 12:57 by miranda